ACUTE PORTOMESENTERIC VENOUS THROMBOSIS FOLLOWING LAPAROSCOPIC SMALL BOWEL RESECTION AND VENTRAL HERNIA REPAIR


Molecular pathways of pannexin1-mediated neurotoxicity

Pannexin1 (Panx1) forms nonselective membrane channels, structurally similar to gap junction pentair hose hemichannels, that is permeable to ions, nucleotides and other small molecules below 900 Da.Panx1 activity is implicated in paracrine signaling and inflammasome regulation.Recent studies in different animal models showed that Panx1 overactivati

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